The Alpha-Synuclein (61-95 aa) antibody (clone 5C2) from MyBioSource.com is a Mouse Monoclonal antibody to NACP, Snca, Synuclein alpha, and Synuclein, alpha. This antibody recognizes Human antigen. The Alpha-Synuclein (61-95 aa) antibody (clone 5C2) has been validated for the following applications: ELISA, and Western Blot.
Description
alpha-synuclein (amino acids 1-140), an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-synuclein has been suggested to be implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders, and more recently, to be an important regulatory component of vesicular transport in neuronal cells. Specially, the non-Abeta component of amyloid plaques (NAC, amino acids 61-95) is a highly amyloidogenic peptide consisting of 35 amino acids which was first identified associated with senile plaques in the Alzheimer's disease brain